Researchers from the University of Nottingham developed a gel that regenerates dental enamel by mimicking its natural formation.
It acts as a matrix that attracts calcium and phosphate from saliva, forming a new mineral layer.
Unlike traditional treatments, it rebuilds enamel instead of replacing it.
In lab tests, it created a layer with properties similar to natural enamel.
It may help to:
- repair early lesions
- protect exposed dentin
- reduce sensitivity
Potential use: prevention and treatment of enamel wear and early caries.
Still requires more studies before widespread clinical use.
Source
Compendium of Continuing Education in Dentistry
Advances in Direct Dental Restorations: Materials and Technology Trends for 2026
Vol. 47, Issue 1 — January/February 2026

