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From cavities to sleep apnea: Dentists can assume new role in saving lives

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A patient dozes off in a dental chair despite the anxiety of an impending procedure. A seemingly unremarkable act but — for dentists versed in the latest sleep research — this red flag hints at a life-threatening condition.

In a research review published in the Journal of the American Dental Association, Rutgers Health researchers identified dentists as an unexpected player in the battle against life-threatening sleep disorders.

The review suggests dental professionals have unique opportunities to screen for conditions such as obstructive sleep apnea, a disorder that affects millions of Americans and is linked to serious health risks, including cardiovascular disease and neurodegeneration.

It also challenges dentists to look beyond teeth and gums to the broader landscape of patient health.

“We have a great opportunity to change lives for the better,” said Davis Thomas, a clinical associate professor at the Rutgers School of Dental Medicine and senior author of the review. “Dentists can be the first line of defense in identifying sleep disorders. They often see symptoms long before physicians. Indicators like tooth grinding, tongue scalloping or even a patient dozing off in the chair can be early signs that something more is going on.”

Sleep disorders such as obstructive sleep apnea affect more than half of Americans at some point in their lives. Many cases go undiagnosed, but dentists can play an important role in reducing those numbers.

The review outlines several key indicators that dental clinicians should look for during examinations, including enlarged jaw muscles, scalloped tongue edges, white lines on the cheeks, restricted visibility of the throat, dental wear patterns and tiny cracks on teeth.

These physical signs, combined with patient history and simple screening tools, can help dentists identify at-risk patients with up to 80 percent accuracy.

“It’s not just about looking at teeth anymore,” Thomas said. “We need to observe the whole patient, from their behavior in the waiting room to the subtle signs in their oral cavity.”

Another sign of concern, according to the review authors, is bruxism, commonly known as teeth grinding. Contrary to long-held beliefs, the studies suggest teeth griding is often a symptom of underlying sleep issues rather than a standalone problem caused by dental misalignment.

“We’ve been treating the symptoms without addressing the root cause for far too long,” Thomas said. “By understanding the neuroscience behind sleep disorders, we can provide more comprehensive care and potentially prevent serious health complications.”

This shift in perspective could have far-reaching implications. By identifying patients at risk for sleep disorders, dentists can facilitate early intervention, potentially preventing complications such as hypertension, heart disease and stroke.

To implement these findings, Thomas and his team propose a simple protocol for dental practices: Incorporate sleep-related questions into patient history forms. Other recommendations include training dental staff to recognize physical signs of sleep disorders and using validated screening tools like the STOP-BANG (snoring, tiredness, observed apnea, blood pressure, body mass index, age, neck size, gender) questionnaire, which screens for obstructive sleep apnea and establish referral networks with sleep medicine specialists.

“We’re not asking dentists to diagnose sleep disorders,” Thomas said. “We’re asking them to recognize the signs and make appropriate referrals. This simple act can be lifesaving.”

Thomas recommends that dentists looking to incorporate sleep screening into their practices start with education.

“Attend sleep medicine conferences, take continuing education courses, and stay up-to-date with the latest research,” he said. “The more we learn, the more we realize how much we don’t know — and how much we can do to help our patients.”

Source: https://www.sciencedaily.com/releases/2024/09/240903144821.htm

Nanometric robots can deeply clean teeth

Nanometric robots controlled by a magnetic field can kill bacteria in dentinal tubules and increase the success rate of root canal treatment, according to researchers from the Indian Institute of Science (IISc) and Tranautilus, a company affiliated with IISc.

Root canal treatment is routinely performed to treat dental infections in millions of patients. The procedure involves removing the infected soft tissue from the tooth, known as the pulp, and flushing the tooth with antibiotics and chemicals to kill the bacteria causing the infection. However, this treatment often does not completely eliminate bacteria (especially antibiotic-resistant bacteria, such as Enterococcus faecalis) that hide in the microscopic grooves of the tooth called dentinal tubules.

“Root canals are very small, and the bacteria live deep in the tissues. Current technology cannot penetrate deep enough to kill them,” explains Shanmukh Srinivas, a researcher at the Centre for Nanoscience and Engineering (CeNSE) at IISc and co-founder of Theranautilus.

The team has now developed spiral-shaped nanorobots made of iron-coated silica that can be controlled by a device generating low-intensity magnetic fields (Advanced Healthcare Materials). They inserted these nanorobots into a sample of extracted teeth and tracked their movement under a microscope.

“By adjusting the frequency of the magnetic field, they were able to move the nanorobots randomly and allow them to penetrate deep into the dentinal tubules. They can also be removed from the patient’s teeth,” says Srinivas.

NO OTHER TECHNOLOGY CAN DO THIS

“Essentially, the magnetic field can be manipulated to generate heat on the surface of the nanorobot, killing nearby bacteria,” says Debayan Dasgupta, a researcher at CeNSE and co-founder of Theranautilus. “No other technology on the market today can do this.”

Traditionally, to enhance the effectiveness of root canal treatment, shock waves were introduced into the fluid via ultrasound or laser pulses to remove bacteria and tissue debris. However, these pulses only penetrate to a depth of about 800 micrometers, and their energy dissipates quickly. As a result, the nanorobots were able to penetrate even deeper, up to 2000 micrometers. The researchers also said that using heat to kill bacteria is a safer alternative to chemicals and antibiotics.

Theranautilus is the result of several years of research on magnetically controlled nanoparticles conducted in Professor Ambarish Ghosh’s lab at CeNSE. Along with his colleagues, his group has already demonstrated that these nanoparticles use light to trap and move objects, float in blood and living cells, and firmly attach to cancer cells. “These studies have shown that they are safe for use in living tissues,” says Dasgupta.

The research team tested the dental nanorobots in a mouse model and found that they were safe and effective. They are also working on a new type of medical device that can be easily carried in the mouth, allowing dentists to insert and manipulate nanobots inside teeth during root canal treatment.

Ghosh says, “The clinical application of this technology, which was considered futuristic just three years ago, is now around the corner. It’s exciting to see simple scientific curiosity turn into a medical intervention that could impact millions of people in India alone.”